TABLE 2

Univariable relationships with bronchial hyperresponsiveness (BHR)

ExposureBHR
OR95% CIp-value
BMI (n=683)1.051.01–1.090.03
Female sex (n=340)1.991.32–3.01 0.001
%ΔFVC (n=599)1.331.23–1.44<0.001
Asthma status
 Never asthma (n=370)1.00
 Remitted asthma (n=160)3.532.08–6.02<0.001
 Current asthma (n=151)8.405.01–14.08<0.001
Smoker
 Never (n=322)1.00
 Former (n=249)0.910.57–1.460.70
 Current (n=112)1.871.09–3.200.02
Social class
 Level 1 (highest) (n=230)1.00
 Level 2 (n=83)0.840.42–1.680.61
 Level 3 (n=144)0.730.39–1.350.31
 Level 4 (n=111)1.090.59–2.040.78
 Level 5 (n=113)2.161.21–3.840.01
Atopy (n=674)2.371.49–3.72<0.001
ICS use (n=678)3.812.32–6.25<0.001
Baseline FEV1/FVC (n=683)0.890.85–0.94<0.001
Family history of asthma
 Neither parent (n=481)1.00
 Either or both parents (163)1.781.12–2.850.02

BMI: body mass index; (Δ)FVC: (change in) forced vital capacity; ICS: inhaled corticosteroid; FEV1: forced expiratory volume in 1 s.