Univariable and multivariable Cox regression analysis of low-risk criteria assessed at first re-evaluation in the subset of patients with available brain natriuretic peptide (BNP) or N-terminal pro-brain natriuretic peptide (NT-proBNP) measurements
| Univariable analysis | Multivariable analysis | |||
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | |
| WHO/NYHA FC I–II | 0.28 (0.19–0.42) | <0.001 | 0.47 (0.32–0.71) | <0.001 |
| 6-min walking distance >440 m | 0.17 (0.09–0.31) | <0.001 | 0.32 (0.17–0.60) | <0.001 |
| BNP <50 ng·L−1 or NT-proBNP <300 ng·mL−1 | 0.21 (0.13–0.34) | <0.001 | 0.31 (0.19–0.52) | <0.001 |
| Right atrial pressure <8 mmHg | 0.45 (0.31–0.65) | <0.001 | ||
| Cardiac index ≥2.5 L·min−1·m−2 | 0.44 (0.30–0.65) | <0.001 | ||
WHO: World Health Organization; NYHA: New York Heart Association; FC: functional class.