TABLE 3

Change in functional class (FC), exercise capacity and haemodynamics between baseline and first re-evaluation

BaselineFirst re-evaluation#p-value
WHO/NYHA FC
 I–II261 (26)595 (59)<0.001
 III624 (61)349 (34)
 IV132 (13)73 (7)
6-min walking distance m311±145354±145<0.001
Haemodymamics
 RAP mmHg8.6±5.07.5±4.8<0.001
 mPAP mmHg50±1344±13<0.001
 Cardiac output L·min−14.4±1.45.3±1.6<0.001
 Cardiac index L·min−1·m−22.4±0.72.9±0.8<0.001
 PVR Wood units10.5±5.97.1±4.6<0.001
SvO2 %63±1067±8<0.001

Data are presented as n (%) or mean±sd, unless otherwise stated. n=1017. WHO: World Health Organization; NYHA: New York Heart Association; RAP: right atrial pressure; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance; SvO2: mixed venous oxygen saturation. #: 5.6±3.4 months after baseline.