TABLEĀ 6

Acquired drug resistance

DrugParticipants evaluated for acquired resistanceParticipants with acquired resistance/evaluated, stratified by treatment outcome
Success#Failure/relapseLoss to follow-up
Fluoroquinolones100/31/50/2
Kanamycin180/52/100/3
Ethionamide11/1
Pyrazinamide11/1
Clofazimine90/22/7

Data are presented as n or n/n from three studies with individual patient data. All acquired resistance was observed in four participants (Bangladesh, n=2; Uzbekistan, n=1; Swaziland, n=1). #: successfully treated participants who had drug susceptibility tests performed on positive cultures obtained during treatment.