TABLE 1

Clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) and healthy donors

ControlsCOPD patients
Subjects n831
Sex male:female n:n4:414:17
Age# years44 (24–58)58 (40–64)
BMI kg·m-224 (22–27)22 (20–25)
FEV1 %NA20 (16–28)
DLCO %NA25 (19–32)
mPAP mmHgNA30 (24–39)
LTOT L·min−1NA3 (3–4)
PO2 mmHgNA63 (60–69)
PCO2 mmHgNA47 (39–58)
PO2/FIO2NA188 (158–216)

Data are presented as median (interquartile range), unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide; mPAP: mean pulmonary arterial pressure; LTOT: long-term oxygen therapy; PO2: oxygen tension; PCO2: carbon dioxide tension; FIO2: inspiratory oxygen fraction; NA: not applicable. #: data are presented as median (range).