TABLE 1

Baseline characteristics of the study population

Total populationNo COPDCOPD
Subjects n21971975222
Age years69.7±6.769.5±6.771.2±7.1
Female51.352.342.3
Ever-smoker68.567.181.1
Smoking pack-years#22.6±21.521.4±21.132.1±21.6
Body mass index kg·m−227.9±4.027.9±4.027.2±3.7
Hypertension73.973.478.4
Diabetes mellitus12.611.819.8
Heart failure3.12.56.5
Left ventricular systolic function %40.0±6.240.2±6.138.1±7.5
DLCOc/VA mmol·min−1·kPa−1·L−11.5±0.21.5±0.21.3±0.3
PASP mmHg26.0±7.025.7±6.729.2±8.7
FEV1 % predicted103.3±19.8106.1±17.779.8±21.0
Pulmonary artery diameter mm26.0±3.725.9±3.626.7±4.1
Aorta diameter mm36.9±3.936.9±3.937.5±3.7
PA:A0.71±0.100.71±0.100.72±0.11

Data are presented as mean±sd or %, unless otherwise stated. Entries represent original data without imputed values. In the total population, values were missing for smoking (2.2%), smoking pack-years (4.6%), body mass index (0.9%), hypertension (0.3%), diabetes mellitus (6.0%), heart failure (1.9%), left ventricular systolic function (3.4%), diffusing capacity of the lung for carbon monoxide, corrected for haemoglobin (DLCOc)/alveolar volume (VA) (40.4%), pulmonary artery systolic pressure (PASP) (58.1%) and forced expiratory volume in 1 s (FEV1) % predicted (11.3%). COPD: chronic obstructive pulmonary disease; PA:A: pulmonary artery to aorta ratio. #: pack-years are presented for former and current smokers only; : measurements were performed between 2009 and 2012.