Parameter | Hazard ratio | Standard error | p-value | 95% confidence interval |
Sex | 0.762 | 0.319 | 0.518 | 0.335–1.733 |
Geographical origin | 1.596 | 0.609 | 0.220 | 0.755–3.373 |
Age at sarcoidosis diagnosis | 1.030 | 0.016 | 0.065 | 0.998–1.062 |
Age at stage 4 diagnosis | 1.036 | 0.016 | 0.029 | 1.003–1.069 |
Age at CPA diagnosis | 1.054 | 0.017 | 0.002 | 1.020–1.090 |
Diabetes mellitus | 2.902 | 1.285 | 0.016 | 1.218–6.915 |
Extrapulmonary manifestations | 0.980 | 0.803 | 0.806 | 0.834–1.150 |
Pulmonary hypertension | 3.425 | 1.306 | 0.001 | 1.621–7.235 |
FEV1 | 0.979 | 0.011 | 0.069 | 0.958–1.001 |
FVC | 0.965 | 0.011 | 0.003 | 0.944–0.988 |
DLCO | 0.968 | 0.010 | 0.003 | 0.947–0.988 |
CPI 40 | 0.293 | 0.147 | 0.015 | 0.109–0.784 |
MPA/AAD >1 | 2.347 | 1.020 | 0.050 | 1.001–5.501 |
CT fibrosis >20% | 2.710 | 1.096 | 0.014 | 1.226–5.990 |
CT fibrosis extent | 1.041 | 0.012 | 0.001 | 1.017–1.066 |
Walsh's algorithm | 3.069 | 1.696 | 0.042 | 1.038–9.068 |
FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; CPI: composite physiological index; MPA/AAD: main pulmonary artery/ascending aorta diameter ratio; CT: computed tomography.