Differences in tidal breathing parameters after breathing 100% oxygen.
| Air | 100% oxygen | Difference (100% oxygen – air) | ||
| Mean (95% CI) | % | |||
| All subjects (n=43) | ||||
| Breath number | 28.6±7.6 | 33.6±9.9 | 5.1 (1.4; 8.7)# | 17 |
| VT mL | 276.5±58.3 | 263.3±53.8 | −13.2 (−1.1; −25.3)# | −4.8 |
| CVVT % | 29.5±11.1 | 28.8±9.8 | −0.6 (2.2; −3.4) | −2.0 |
| RR min−1 | 24.8±7.3 | 24.0±7.4 | −0.9 (−0.4; −2.1) | −3.6 |
| V′E mL·min−1 | 6449.1±1370.6 | 5913.5±1020.1 | −535.6 (−234.7; −836.5)+ | −8.3 |
| MTEF mL·s−1 | 196.5±47.8 | 179.9±33.9 | −16.6 (−7.7; −25.5)+ | −8.4 |
| MTIF mL·s−1 | 245.8±45.9 | 230.2±37.3 | −15.6 (−7.0; −24.2)+ | −6.3 |
| CO2 emitted mL | 9.2±2.4 | 8.7±2.3 | 0.5 (1.0; 0.1)# | 5.4 |
| Healthy control subjects (n=15) | ||||
| Breath number | 27.5±7.5 | 31.3±7.1 | 3.7 (1.4; −1.6) | 13.5 |
| VT mL | 284.8±65.2 | 263.5±46.2 | −21.2 (−1.0; −41.5)# | −7.4 |
| CVVT % | 28.1±12.2 | 26.8±11.2 | −1.4 (4.1; −6.9) | −5.0 |
| RR min−1 | 22.5±4.9 | 22.0±6.2 | −0.5 (1.6; −2.6) | −2.2 |
| V′E mL·min−1 | 6073.4±1258.1 | 5563.6±962.1 | −509.8 (−14.6; −1005.0)# | −8.4 |
| MTEF mL·s−1 | 191.7±45.2 | 168.5±29.0 | −23.2 (−9.5; −36.8)¶ | −12.1 |
| MTIF mL·s−1 | 236.1±51.5 | 215.5±37.0 | −20.6 (−7.2; −34.1)¶ | −8.7 |
| CO2 emitted mL | 9.3±2.6 | 8.6±2.0 | 0.4 (1.3; 0.2) | 7.5 |
| Subjects with cystic fibrosis (n=28) | ||||
| Breath number | 29.1±7.7 | 34.9±11.1 | 5.8 (10.9; 0.7)# | 13.5 |
| VT mL | 272.1±55.0 | 263.2±58.3 | −8.9 (6.9; −24.6) | −3.3 |
| CVVT % | 30.2±10.5 | 29.9±9.0 | −0.2 (3.2; −3.6) | −0.7 |
| RR min−1 | 26.1±8.1 | 25.0±7.8 | −1.0 (0.5; −2.6) | −3.8 |
| V′E mL·min−1 | 6650.4±1407.4 | 6101.0±1017.1 | −549.4 (−147.9; −950.9)¶ | −8.3 |
| MTEF mL·s−1 | 199.0±49.8 | 186.0±35.2 | −13.1 (−1.0; −25.1)# | −6.6 |
| MTIF mL·s−1 | 251.0±42.8 | 238.1±35.6 | −12.9 (−1.4; −24.5)# | −5.1 |
| CO2 emitted mL | 9.1±2.3 | 8.7±2.5 | 0.7 (1.3; 0.1)# | 7.7 |
Data are presented as mean±sd, unless otherwise stated. Bold indicates statistically significant values. Between measurement comparisons of tidal volume (VT), coefficient variation of VT (CVVT), respiratory rate (RR), minute ventilation (V′E), mean tidal expiratory flow (MTEF) and mean tidal inspiratory flow (MTIF). #: p<0.05; ¶: p<0.01; and +: p=0.001.