TABLE 2

Differences in microbial community composition between niches

OTUsq valuep valueRelative abundance %
All three nichesNP-BALOP-BALNPOPBAL
Streptococcus (1)0.0060.0120.84217.534.230.2
Moraxella0.3930.7080.86220.40.48.9
Neisseria0.0110.0070.9562.510.67.6
Staphylococcus aureus0.0040.9410.0079.60.18.5
Streptococcus (2)0.0200.0510.8202.55.83.5
Veillonella dispar0.0010.0020.6980.85.14.0
Prevotella melaninogenica0.0080.0180.8780.66.92.3
Rothia mucilaginosa<0.0010.0030.2031.15.82.5
Gemellaceae0.005<0.0010.6142.72.64.1
Haemophilus influenzae0.2420.3980.4154.40.03.9
Dolosigranulum0.1360.4380.8876.90.00.0
Corynebacterium (1)0.0030.0400.9846.30.00.0
Corynebacterium (2)0.0100.0850.9625.70.00.0
Prevotella0.0280.0220.8080.22.42.3
Lactobacillales0.0050.0060.9420.81.51.4
Porphyromonas (1)0.0110.0100.9950.22.01.2
Streptococcus (3)0.0020.0160.3140.31.90.8
Actinomyces<0.0010.0020.5000.41.70.8
Corynebacterium (3)0.6200.9670.9692.30.00.0
Porphyromonas (2)0.0040.0150.9010.00.91.4
  • This table depicts the differences with regard to the 20 most abundant OTUs between NP, OP and BAL samples (n=25 each) calculated by Kruskal–Wallis, with Benjamini–Hochberg correction for multiple testing (q value) and Nemenyi post hoc tests (only considering NP–BAL and OP–BAL comparisons). p<0.05 are shown in bold. OTU: operational taxonomic units; NP–BAL: comparison between nasopharyngeal and bronchoalveolar lavage samples; OP–BAL, comparison between oropharyngeal and bronchoalveolar lavage samples; NP: nasopharyngeal; OP: oropharyngeal; BAL; bronchoalveolar lavage.