TABLE 2

What are the most important outcomes to consider when making decisions on the treatment of drug-resistant tuberculosis (TB)?

OutcomesMean score
Adherence to TB treatment (treatment interruption due to nonadherence)6.8
Avoiding adverse reactions from TB drugs7.0
Avoiding the acquisition or amplification of drug resistance7.9
Cure or successful completion by end of treatment9.0
Culture conversion by month 67.4
Death (survival) by the end of projected treatment8.1
Treatment failure8.7
Relapse7.7
  • Members of the Guideline Development Group scored TB outcomes according to their relative priority when making decisions on drug-resistant TB treatment. They were asked to take a societal perspective in rating the outcomes. 1–3 points: not important for making recommendations on drug-resistant TB treatment; 4–6 points: important but not critical for making recommendations on drug-resistant TB treatment; 7–9 points: critical for making recommendations on drug-resistant TB treatment.