Characteristic | MPR data available | No MPR data available | p-value |
Subjects n | 106 | 143 | |
Age years | 29.8±8.2 | 29.5±9.8 | 0.8 |
Male | 46 (43.4) | 57 (39.9) | 0.6 |
Genotype | |||
F508/F508 | 72 (68.0) | 81 (56.7) | 0.1 |
F508/heterozygous | 31 (29.2) | 1 (35.6) | |
Other | 3 (2.8) | 11 (7.7) | |
Cystic fibrosis related diabetes | 17 (16) | 11 (7.7) | 0.04 |
Microbiological status | |||
Non-Pseudomonas | 23 (21.7) | 32 (22.4) | 0.2 |
Pseudomonas | 75 (70.8) | 88 (61.5) | |
Burkholderia cepacia | 5 (4.7) | 12 (8.4) | |
Mycobacterium abcessus | 3 (2.8) | 11 (7.7) | |
Weight kg | 64.0±13.6 | 64.3±13.7 | 0.9 |
BMI kg·m−2 | 22.4±3.6 | 22.6±4.0 | 0.6 |
FEV1 % predicted | 60.2±24.5 | 62.4±25.9 | 0.5 |
FVC % predicted | 78.7±22.1 | 80.2±24.0 | 0.6 |
HbA1c mmol·mol−1 | 45.2±13.8 | 44.5±12.1 | 0.7 |
Days treated with i.v. antibiotics (preceding 12 months) | 29.1±40.0 | 28.0±39.4 | 0.8 |
Number of medications | 13.8±4.5 | 13.1±4.7 | 0.3 |
Data are presented as mean±sd or n (%) unless otherwise stated. A two-sample t-test was used for normally distributed variables and Pearson's Chi-squared test for categorical variables. MPR: medication possession ratio; BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; HbA1c: haemoglobin A1c; i.v.: intravenous.