TABLE 2

Numbers of events and hazard ratio (HR) of individual cardiovascular diseases (CVDs) comparing patients with sarcoidosis with subjects without sarcoidosis

Events after index date for cases/comparatorsCumulative incidence (95% CI) at 10 yearsHR (95% CI)#HR (95% CI)
CasesComparators
Coronary artery disease54/388.3 (5.0–11.5)5.3 (2.6–7.9)1.55 (1.02–2.35)1.58 (0.89–2.80)
Congestive heart failure45/247.6 (4.5–10.7)1.8 (0.2–3.4)2.06 (1.25–3.38)2.72 (1.46–5.06)
Atrial fibrillation33/184.6 (2.0–7.1)2.2 (0.4–4.0)1.93 (1.08–3.43)1.90 (0.97–3.93)
Cerebrovascular accident32/145.2 (2.6–7.7)0.6 (0.0–1.4)2.51 (1.34–4.71)3.32 (1.53–7.18)
Transient ischaemic attack6/41.0 (0.0–2.2)0.4 (0.0–1.1)1.68 (0.47–5.96)2.12 (0.33–13.62)
Peripheral arterial disease13/92.0 (0.4–3.6)0.6 (0.0–1.4)1.55 (0.66–3.63)2.09 (0.68–6.42)
Abdominal aortic aneurysm4/41.0 (0.0–2.1)0.6 (0.0–1.5)1.13 (0.28–4.53)1.83 (0.26–12.60)
Any CVD96/6517.6 (12.9–22.0)8.1 (4.8–11.3)1.57 (1.15–2.16)1.65 (1.08–2.53)
  • Data are presented as n/n or %, unless otherwise stated. #: for all events after index date, adjusted for age, sex and calendar year; : for all events after index date, adjusted for age, sex, calendar year, current smoking, diabetes mellitus, hypertension, dyslipidaemia and obesity.