TABLE 4

Within-trial treatment and follow-up costs (average cost per randomised patient)

	Standard care	Telemedicine	Difference		ICER (EUR per QALY)
	Standard care	Telemedicine	EUR	p-value^#	ICER (EUR per QALY)
Subjects	48	52
Direct costs EUR
Telemonitoring^¶	0	23.75	−23.75	<0.001
Sleep unit visits and consultations	69.25	6.73	62.52	<0.001
CPAP provider visits and consultations	14.38	20.39	−6.01	0.003
Changes in CPAP device components	79.52	69.13	10.39	0.315
Total	163.15	119.99	43.16	0.012
Indirect costs EUR
Patient travel costs to sleep unit	6.49	0.18	6.31	<0.001
Patient travel costs to CPAP provider	1.33	3.48	−2.15	0.027
Total	7.82	3.66	4.16	0.002
Average total cost per patient EUR	170.97	123.65	47.32	0.022	17 358.65

Data are presented as n, unless otherwise stated. Costs based on the Catalan Institute of Health [20] or supplied by the CPAP provider. ICER: incremental cost-effectiveness ratio; QALY: quality-adjusted life-year; CPAP: continuous positive airway pressure. ^#: Mann–Whitney two-sample statistic; ^¶: including 2G (GSM/GPRS) daily data transfer and alarm management costs.