Sensitivity and specificity of the 11 studies directly addressing the PICO question using transmission electron microscopy to diagnose primary ciliary dyskinesia
| First author [ref.] | Study population n | Conclusive diagnostic result reached n | Sensitivity (95% CI) | Specificity (95% CI) |
| Jorissen [37] | 812 | 468 | 0.71 (0.61–0.81) | 1.0 (0.99–1.0) |
| Pifferi [52] | 64 | 62 | 0.75 (0.48–0.93) | 1.0 (0.93–1.0) |
| Pifferi [39] | 59 | 56 | 0.77 (0.50–0.93) | 1.0 (0.91–1.0) |
| Hirst [53] | 231 | 187 | 1.0 (0.88–1.0) | 1.0 (0.98–1.0) |
| Papon [54] | 1149 | 793 | 0.82 (0.77–0.86) | 1.0 (0.99–1.0) |
| Olm [55] | 24 | 24 | 0.92 (0.62–1.0) | 1.0 (0.74–1.0) |
| Papon [42] | 34 | 28 | 0.83 (0.52–0.98) | 1.0 (0.79–1.0) |
| Shoemark [56] | 1182 | 1031 | 0.88 (0.83–0.91) | 1.0 (1.0–1.0) |
| Hirst [40] | 165 | 122 | 0.96 (0.87–1.0) | 1.0 (0.95–1.0) |
| Munkholm [57] | 239 | 61 | 0.83 (0.61–0.95) | 0.92 (0.79–0.98) |
| Jackson [26] | 868 | 368 | 0.79 (0.68–0.88) | 1.0 (0.99–1.0) |