Characteristics | Registry linkage# | MoBa¶ | ||
n | % pre-eclampsia | n | % pre-eclampsia | |
Pre-eclampsia | ||||
No | 390 578 | 43 281 | ||
Yes | 16 329 | 4.0 | 1747 | 3.9 |
Maternal age at delivery years | ||||
<25 | 70 123 | 4.9 | 4996 | 5.5 |
25–29 | 137 239 | 4.1 | 15 457 | 4.3 |
30–34 | 135 788 | 3.5 | 17 300 | 3.2 |
35+ | 63 757 | 3.9 | 7275 | 3.4 |
Maternal parity | ||||
Nulliparous | 164 683 | 5.9 | 19 511 | 5.6 |
1 | 146 081 | 2.8 | 16 045 | 2.6 |
2 | 68 174 | 2.6 | 7407 | 2.4 |
3+ | 27 969 | 2.7 | 2065 | 3.0 |
Maternal education | ||||
Less than secondary school | 77 340 | 4.2 | 3789 | 4.5 |
Secondary school | 148 773 | 4.4 | 14 479 | 4.4 |
Up to 4 years of university | 137 854 | 3.9 | 18 387 | 3.6 |
More than 4 years of university | 29 950 | 3.1 | 8206 | 3.3 |
Missing | 12 990 | 2.7 | 167 | 5.4 |
Maternal asthma | ||||
No | 389 995 | 4.0 | 43 199 | 3.8 |
Yes | 16 912 | 5.3 | 1829 | 5.2 |
Maternal smoking at start of pregnancy | ||||
No | 268 177 | 4.1 | 39 868 | 4.0 |
Yes | 72 409 | 3.4 | 4968 | 2.8 |
Missing | 66 321 | 4.2 | 192 | 2.1 |
Maternal pre-pregnancy BMI | ||||
Underweight (<18.5) | NA | 1253 | 2.4 | |
Normal weight (18.5–24.9) | NA | 28 421 | 2.7 | |
Overweight (25–29.9) | NA | 9865 | 5.2 | |
Obese (≥30) | NA | 4238 | 8.7 | |
Missing | NA | 1251 | 4.6 | |
Year of birth | ||||
1999 | 55 155 | 4.3 | ||
2000 | 54 974 | 4.2 | 1102 | 4.5 |
2001 | 52 630 | 4.1 | 3265 | 4.2 |
2002 | 51 643 | 4.3 | 6878 | 4.3 |
2003 | 52 861 | 3.7 | 10 060 | 3.6 |
2004 | 53 459 | 3.7 | 10 632 | 3.9 |
2005 | 53 347 | 3.8 | 11 828 | 3.7 |
2006 | 32 838 | 3.9 | 1263 | 3.6 |
Child gender | ||||
Male | 208 643 | 4.1 | 22 975 | 3.9 |
Female | 198 264 | 4.0 | 22 053 | 3.8 |
Preterm birth | ||||
No | 385 458 | 3.2 | 42 997 | 3.1 |
Yes | 21 449 | 18.0 | 2031 | 19.5 |
There were significant differences in the distribution of pre-eclampsia by all maternal and child characteristics (p<0.003) except for child's sex (p=0.109 in the registry linkage and p=0.639 in MoBa). MoBA: Norwegian Mother and Child Cohort Study; BMI: body mass index. #: n=406 907; ¶: n=45 028.