TABLE 2

The annual change in lung function between Max0–2.5 and follow-up visit

<10 pack-years≥10 pack-yearsp-value
Subjects12465
ΔFEV1 mL·year–1−36.1 (−60.7–  −21.6)−54.1 (−73.2–  −32.6)0.003#
ΔFEV1 % pred·year–1−0.34 (−1.04–0.34)−0.75 (−1.25–  −0.23)0.006#
ΔFEV1/FVC·year–1−0.004 (−0.007–  −0.002)−0.006 (−0.009–  −0.003)0.045#
ΔFVC mL·year–1−27.6 (−54.9–  −6.8)−41.7 (−63.2–  −20.8)0.035#
ΔFVC % pred·year–10.05 (−0.68–0.78)−0.12 (−0.62–0.44)0.411
  • Data are presented as n or median (interquartile range), unless otherwise stated. Max0–2.5: point of highest lung function (forced expiratory volume in 1 s (FEV1) % pred) during the first 2.5 years after baseline; FVC: forced vital capacity. #: statistically significant at p<0.05.