TABLE 2

Description of mutations and translocations in EGFR and ALK

Gene
EGFR
 Analysis performed209 (64.7)
 Not analysed114 (35.3)
 Mutated#90 (42.0)
 Nonmutated#119 (58.0)
 Mutation type
  Exon 18 (G719X)0 (0)
  Exon 19 deletion49 (56.2)
  Exon 20 (S768I)0 (0)
  Exon 20 (T790M)2 (2.3)
  Exon 20 insertion3 (3.4)
  Exon 21 (L858R)34 (39.1)
ALK
 Analysis performed80 (24.8)
 Not analysed243 (75.2)
 Translocated12 (15.0)
 Nontranslocated68 (85.0)
  • Data are presented as n (%) unless otherwise stated. #: three participants had EGFR mutations but mutation type was not recorded; : two participants displayed more than one mutation.