Residential radon concentration, EGFR mutations and ALK translocations
Gene | Patients n | Residential radon concentration Bq·m−3 | p-value |
EGFR | |||
Mutated | 90 | 160 (100–306) | 0.932 |
Nonmutated | 119 | 174 (96–295) | |
EGFR mutation type | |||
Exon 18 (G719X) | |||
Exon 19 deletion | 49 | 216 (103–412) | |
Exon 20 (S768I) | |||
Exon 20 (T790M) | 2 | 70 | 0.329# |
Exon 20 insertion | 3 | 150 | 0.057¶ |
Exon 21 (L858R) | 34 | 118 (98–266) | |
Two mutations | 2 | 224 | |
ALK | |||
Rearranged | 12 | 290 (63–352) | 0.958 |
Not rearranged | 68 | 164.5 (105–295) |
Data are presented as median, p25–p75. #median test comparing all EGFR mutations; ¶: median test comparing only exon 19 deletions with exon 21 (L858R) single-point substitution mutations.