TABLE 3

Residential radon concentration, EGFR mutations and ALK translocations

GenePatients nResidential radon concentration Bq·m−3p-value
EGFR
 Mutated90160 (100–306)0.932
 Nonmutated119174 (96–295)
EGFR mutation type
 Exon 18 (G719X)
 Exon 19 deletion49216 (103–412)
 Exon 20 (S768I)
 Exon 20 (T790M)2700.329#
 Exon 20 insertion31500.057
 Exon 21 (L858R)34118 (98–266)
 Two mutations2224
ALK
 Rearranged12290 (63–352)0.958
 Not rearranged68164.5 (105–295)
  • Data are presented as median, p25–p75. #median test comparing all EGFR mutations; : median test comparing only exon 19 deletions with exon 21 (L858R) single-point substitution mutations.