TABLE 2

Gastro-oesophageal reflux (GOR) symptoms and hiatal hernia at diagnosis of interstitial lung disease of the 182 patients

IPFCHPSScNon-SSc CTDp-value
Subjects79321754
GOR symptoms36/78 (46)5/22 (23)8/13 (62)9/35(26)0.034
Patients treated with a PPI57/77 (74)18/31 (58)15/17 (88)26/52 (50)0.029
Presence of hiatal hernia on CT scan42/79 (53)9/32 (28)10/17 (59)18/54 (33)0.017
Presence of type II, III or IV hiatal hernia11/79 (14)1/32 (3)1/17 (6)1/54 (2)0.005
Oesophageal or intra-thoracic stomach area mm2339 (75–6406)254 (94–659)505 (150–1648)243 (102–650)0.014
Presence of air in the oesophagus72/79 (91)27/32 (84)17/17 (100)51/54 (94)0.229
Presence of food/fluid/air-fluid level in the oesophagus7/79 (9)2/32 (6)5/17 (29)1/54 (2)0.005
  • Data are presented as n, n/N (%) or median (range), unless otherwise stated. IPF: idiopathic pulmonary fibrosis; CHP: chronic hypersensitivity pneumonitis; SSc: scleroderma; CTD: connective tissue disease; PPI: proton pump inhibitor; CT: computed tomography.