Age-adjusted correlations between telomere length and oxidative stress markers and α1-antitrypsin (AAT) levels in α1-antitrypsin deficiency (AATD) patients and controls
| Controls | AATD patients | |||
| Spearman's Rho | p-value | Spearman's Rho | p-value | |
| AAT mg·dL−1 | −0.231 | 0.340 | 0.374 | 0.002 |
| MDA pmol·mg−1 | 0.207 | 0.694 | −0.378 | 0.043 |
| 8-OHdG ng·mL−1 | −0.399 | 0.159 | −0.347 | 0.041 |
| PC nmol·mg−1 | −0.039 | 0.933 | −0.061 | 0.680 |
| H2O2 fluorescence units | 0.393 | 0.263 | −0.202 | 0.008 |
Correlations were assessed with Spearman's rank test. A p-value <0.05 was statistically significant. MDA: malonyldialdehyde; 8-OHdG: 8-hydroxydeoxyguanosine; PC: protein carbonyls; H2O2: hydrogen peroxide.