Relationship between variables and acute exacerbations in the cohort of elderly asthmatics
| Experience of acute exacerbation at 1 year (no versus yes)# | ||
| β coefficient | p-value | |
| Age | 0.045 | 0.401 |
| Sex_male | −1.175 | 0.179 |
| BMI | −0.101 | 0.258 |
| Smoking status_yes | 1.651 | 0.043 |
| FEV1 % predicted | −0.016 | 0.412 |
| History of acute exacerbation_yes | 1.549 | 0.091 |
| Cognitive function | 0.022 | 0.802 |
| Depression | 0.172 | 0.062 |
| ln(PC20) | 0.292 | 0.359 |
| ln(DRS) | 0.727 | 0.696 |
| ln(CIR) | 0.165 | 0.886 |
| ln(PRI) | 4.079 | 3.43×10−3 |
BMI: body mass index; FEV1: forced expiratory volume in 1 s; PC20: concentration of methacholine causing a 20% decrease in FEV1 from baseline; DRS: dose–response slope; CIR: continuous index of response; PRI: per cent recovery index. Data in bold indicates statistically significant results (p<0.05). #: Logistic regression analysis.