TABLE 1

Factors associated with diabetes mellitus in the Portuguese population with tuberculosis from 2008 to 2013

Patients nDiabetes mellitusBivariate analysisMultiple analysis
No
n (%)
Yes
n (%)
OR (95% CI)p-valueOR (95% CI)Estimate#Lower bound#Upper bound#
Sex11 3170.4401.044 (0.999–1.088)0.044−0.0010.084
 Male78947410 (69.7)484 (71.1)1.070 (0.902–1.269)
 Female34233226 (30.3)197 (28.9)Reference
Foreign origin11 3170.001
 Yes17871709 (16.1)78 (11.5)0.676 (0.531–0.860)
 No95308927 (83.9)603 (88.5)Reference
Alcohol dependence10 6610.474
 Yes16501557 (15.5)93 (14.5)0.921 (0.734–1.154)
 No90118462 (84.5)549 (85.5)Reference
i.v. drug user10 680<0.0010.603 (0.494–0.729)−0.505−0.706−0.316
 Yes746734 (7.3)12 (1.9)0.241 (0.135–0–429)
 No99349303 (92.7)631 (98.1)Reference
Other drug user10 647<0.0010.643 (0.557–0742)−0.442−0.586−0.299
 Yes880862 (8.6)18 (2.8)0.306 (0.191–0.491)
 No97679143 (91.4)624 (97.2)Reference
Reclusion10 8540.342
 Yes201192 (1.9)9 (1.4)0.723 (0.369–1.417)
 No10 65310 004 (98.1)649 (98.6)Reference
Homelessness10 8510.213
 Yes181174 (1.7)7 (1.1)0.620 (0.290–1.326)
 No10 67010 020 (98.3)650 (98.9)Reference
Communitarian shelter10 8050.651
 Yes329307 (3.0)22 (3.3)1.107 (0.713–1.719)
 No10 4769839 (97.0)637 (96.7)Reference
HIV11 317<0.0010.497 (0.432–0.564)−0.700−0.840−0.573
 Yes11231097 (10.3)26 (3.8)0.345 (0.232–0.513)
 No10 1949539 (89.7)655 (96.2)Reference
Haematological malignancies11 3170.448
 Yes3330 (0.3)3 (0.4)1.564 (0.476–5.139)
 No11 28410 606 (99.7)678 (99.6)Reference
Lung cancer11 3170.708
 Yes117109 (1.0)8 (1.2)1.148 (0.558–2.364)
 No11 20010 527 (99.0)673 (98.8)Reference
Other cancers11 317<0.001
 Yes298262 (2.5)36 (5.3)2.210 (1.546–3.159)
 No11 01910 374 (97.5)645 (94.7)Reference
COPD11 3170.014
 Yes286259 (2.4)27 (4.0)1.654 (1.104–2.478)
 No11 03110 377 (97.6)654 (96.0)Reference
Liver disease11 3170.182
 Yes425393 (3.7)32 (4.7)1.285 (0.889–1.859)
 No10 89210 243 (96.3)649 (95.3)Reference
Renal failure11 317<0.001
 Yes10992 (0.9)17 (2.5)2.934 (1.739–4.952)
 No11 20810 636 (99.1)664 (97.5)Reference
Silicosis11 3170.639
 Yes138131 (1.2)7 (1.0)0.833 (0.388–1.789)
 No11 17910 505 (98.8)674 (99.0)Reference
Sarcoidosis11 3171.000
 Yes1212 (0.1)0 (0)
 No11 30510 624 (99.9)681 (100)
Other diffuse lung disease11 3170.411
 Yes2828 (0.3)0 (0)
 No11 28910 608 (99.7)681 (100)
Inflammatory joint disease11 3170.022
 Yes5850 (0.5)8 (1.2)2.517 (1.188–5.330)
 No11 25910 586 (99.5)673 (98.8)Reference
Abnormal radiograph10 6850.137
 Yes10 3199671 (96.5)648 (97.6)1.466 (0.883–2.434)
 No366350 (3.5)16 (2.4)Reference
Cavitation10 6850.226
 Yes51324798 (47.9)334 (50.3)1.102 (0.942–1.289)
 No55535223 (52.1)330 (49.7)Reference
Fatal adverse drug reaction90310.099
 Yes297273 (3.2)24 (4.5)1.430 (0.933–2.191)
 No87348228 (96.8)506 (95.5)Reference
Isoniazid resistance73480.632
 Yes450419 (6.1)31 (6.6)1.097 (0.752–1.599)
 No68986462 (93.9)436 (93.4)Reference
Rifampicin resistance73490.697
 Yes9388 (1.3)5 (1.1)0.836 (0.338–2.067)
 No72566794 (98.7)462 (98.9)Reference
Ethambutol resistance73420.607
 Yes6560 (0.9)5 (1.1)1.229 (0.491–3.076)
 No72776815 (99.1)462 (98.9)Reference
Pyrazinamide resistance56810.707
 Yes10296 (1.8)6 (1.6)0.853 (0.371–1.958)
 No55795198 (98.2)381 (98.4)Reference
Streptomycin resistance72600.793
 Yes713666 (9.8)47 (10.2)1.043 (0.763–1.425)
 No65479132 (90.2)415 (89.8)Reference
Treatment success10 403<0.001
 Yes96559107 (93.2)548 (86.3)0.457 (0.360–0.581)
 No748661 (6.8)87 (13.7)Reference
Mortality10 403<0.0011.098 (1.031–1.172)0.0940.0310.159
 Yes746659 (6.7)87 (13.7)2.194 (1.727–2.789)
 No96579109 (93.3)548 (86.3)Reference
Age years43.0 (33.0–56.0)+60.0 (50.0–72.0)+1.044 (1.039–1.048)<0.0011.047 (1.046–1.049)0.0460.0450.047
Time from symptoms to diagnosis days60.0 (36.0–102.0)+66.0 (39.0–112.0)+1.000 (1.000–1.001)0.209
  • COPD: chronic obstructive pulmonary disease. #: results from the logistic regression methodology; the “Estimate” column corresponds to the mean of all estimates obtained within the procedure, while the “Lower bound” and “Upper bound” columns correspond to the 0.025 and 0.975 quantiles, respectively; if 0 is not within the given interval, then the variable is statistically significant for a 0.05 significance level. : haemodialysis. +: median (interquartile range).