Summary of baseline demographics: baseline anticoagulant users and nonusers
| Anticoagulant users | Anticoagulant nonusers | p-value | |
| Subjects | 32 | 592 | |
| Age years | 71.1±6.8 | 66.9±7.5 | 0.0025 |
| Male | 24 (75.0) | 441 (74.5) | 0.9489 |
| FVC % pred | 70.0±11.7 | 72.1±13.7 | 0.3996 |
| DLCO % pred | 43.3±8.4 | 45.7±11.2 | 0.1290 |
| 6MWD m | 368.2±109.4 | 414.1±92.9 | 0.0080 |
| UCSD SOBQ score | 38.2±23.8 | 34.7±21.5 | 0.3697 |
| Medical history | |||
| Cardiovascular disease | 14 (43.8) | 153 (25.8) | 0.0259 |
| Chronic renal failure | 3 (9.4) | 17 (2.9) | 0.0419 |
| COPD | 1 (3.1) | 21 (3.5) | 0.8996 |
| Pulmonary embolism | 5 (15.6) | 1 (0.2) | <0.0001 |
| Pulmonary hypertension | 3 (9.4) | 16 (2.7) | 0.0324 |
| Atrial fibrillation | 15 (46.9) | 14 (2.4) | <0.0001 |
| Deep vein thrombosis | 9 (28.1) | 8 (1.4) | <0.0001 |
| Cardiovascular risk factors | |||
| Hypertension | 20 (62.5) | 320 (54.1) | 0.3500 |
| Smoker current/ex | 22 (68.8) | 362 (61.1) | 0.3893 |
| Diabetes | 8 (25.0) | 126 (21.3) | 0.6180 |
| Hypercholesterolaemia | 18 (56.3) | 277 (46.8) | 0.2965 |
| Obese (BMI >30 kg·m−2) | 17 (53.1) | 248 (41.9) | 0.2105 |
Data are presented as n, mean±sd or n (%), unless otherwise stated. FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; 6MWD: 6-min walk distance; UCSD SOBQ: University of California San Diego Shortness of Breath Questionnaire; COPD: chronic obstructive pulmonary disease; BMI: body mass index.