TABLE 5

Patient phenotypic profiles according to cluster analysis

Class
12345
Patients n6267354864
Mean age years66.1 (n=61)62.0 (n=67)70.1 (n=34)65.3 (n=48)70.1 (n=63)
Male83.977.662.966.762.5
Type of usual physical activity
 Housework only33.956.782.981.365.6
 Recreational22.635.88.62.11.6
 Maintenance29.03.02.96.312.5
 Physical training11.34.52.98.318.8
Active smoker29.053.711.450.014.1
BMI kg·m−2
 ≤203.216.417.114.623.4
 20–2546.820.934.339.637.5
 25–3030.623.922.931.329.7
 >3017.738.825.714.69.4
Mean time since diagnosis years4.8 (n=61)5.4 (n=66)12.6 (n=32)7.5 (n=48)10.9 (n=63)
≥1 exacerbation in the past 12 months29.050.774.364.654.7
Mean FEV1 % predicted57.8 (n=62)52.0 (n=66)31.2 (n=34)41.3 (n=48)35.3 (n=64)
IC/TLC ratio
 ≤0.28.114.928.610.434.4
 0.2–0.39.717.911.445.831.3
 >0.343.535.814.320.89.4
 Missing38.731.345.722.925.0
Rehabilitation8.19.02.912.525.0
Oxygen8.16.071.420.853.1
Anxious symptoms11.37.557.191.715.6
Depressive symptoms4.87.531.462.50.0
mMRC grade
 030.61.50.02.10.0
 141.944.80.027.110.9
 212.926.90.027.128.1
 33.24.517.116.732.8
 40.03.065.72.10.0
 Missing11.319.417.125.028.1
SF-12
 Mean PCS44.1 (n=57)38.1 (n=61)25.3 (n=34)33.7 (n=44)26.6 (n=56)
 Mean MCS54.4 (n=57)48.7 (n=61)36.7 (n=34)38.1 (n=44)48.5 (n=56)
  • Data are presented as % unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; IC/TLC: inspiratory capacity/total lung capacity; mMRC: modified Medical Research Council dyspnoea scale; SF-12: 12-item Short-Form Health Survey; PCS: physical composite scale; MCS: mental composite scale.