TABLE 4

Results of scenario analysis

ScenarioIncremental absolute percentage of receiving lung transplantationAdditional life expectancy yearsAdditional quality-adjusted life-yearsIncremental lifetime costs US$
Optimistic−29.53 (−26.44–−33.38)30.59 (27.31–33.68)25.64 (21.79–29.12)3 540 660 (1 310 481–5 507 336)
Intermediate−19.01 (−14.98–−23.01)19.23 (15.15–22.54)15.85 (12.37–18.93)3 388 927 (1 451 385–4 817 945)
Conservative−1.16 (−0.79–−1.59)1.16 (0.91–1.49)0.91 (0.71–1.18)443 814 (−511 469–727 012)
6-year-old−18.50 (−22.05–−14.82)18.09 (14.63–21.13)14.92 (11.92–17.95)3 740 480 (2 199 261–4 915 629)
9-year-old−19.74 (−15.91–−23.59)19.30 (15.39–22.60)15.83 (12.27–19.19)3 517 034 (1 936 263–4 716 440)
12-year-old−20.04 (−15.72–−23.91)19.56 (14.87–23.56)16.03 (12.03–19.57)3 455 593 (1 715 960–4 680 515)
  • Data are presented as n (95% credible interval), ivacaftor plus usual care versus usual care alone.