Patient-related outcomes at inclusion
| mMRC grade | |
| 0 | 7.6 |
| 1 | 27.5 |
| 2 | 20.7 |
| 3 | 14.5 |
| 4 | 9.4 |
| Missing | 20.3 |
| SF-12# | |
| PCS score | 34.4±10.0 (n=252) |
| MCS score | 46.5±11.3 (n=252) |
| CAT total score | |
| Low impact | 14.5 |
| Medium impact | 41.3 |
| High impact | 31.2 |
| Very high impact | 8.0 |
| Missing | 5.1 |
| DIRECT total score¶ | 14.5±8.3 (n=274) |
| HADS | |
| Anxiety score | |
| Normal | 56.5 |
| Mild | 12.7 |
| Moderate | 11.6 |
| Severe | 5.4 |
| Missing | 13.8 |
| Depression score | |
| Normal | 49.3 |
| Mild | 15.6 |
| Moderate | 13.8 |
| Severe | 6.9 |
| Missing | 14.5 |
| K6 total score+ | 22.4±5.1 (n=270) |
| Global assessment of handicap§ | |
| Mild | 8.3 |
| Moderate | 32.6 |
| Severe | 41.3 |
| Very severe | 15.6 |
| Missing | 2.2 |
| Global impression of change since inclusion regarding global handicap§ | |
| Very much/much improved | 10.1 |
| Minimally improved | 33.7 |
| No change | 26.1 |
| Minimally worsened | 5.4 |
| Very much/much worsened | 3.3 |
| Missing | 21.4 |
Data are presented as % or mean±sd, unless otherwise stated. mMRC: modified Medical Research Council dyspnoea scale; SF-12: 12-item Short-Form Health Survey; PCS: physical composite scale; MCS: mental composite scale; CAT: COPD Assessment Test; DIRECT: Disability Related to COPD Tool; HADS: Hospital Anxiety and Depression Scale; K6: Kessler's 6-question scale for assessment of nonspecific psychological distress. #: higher score=better health status; ¶: range 0–34, higher score=higher level of disability; +: range 6–30, higher score=less severe psychological distress; §: self-evaluated.