Presence of one or more pulmonary arteriovenous malformations (PAVMs) on chest computed tomography at screening
| PAVM | No PAVM | |
| Total | 37 (18.9) | 159 (81.1) |
| Subgroup | ||
| No RLS | 0 (0) | 85 (100.0) |
| Grade 1 | 8 (13.6) | 51 (86.4) |
| Grade 2 | 12 (36.4) | 21 (63.6) |
| Grade 3 | 17 (89.5) | 2 (10.5) |
Data are presented as n (%). n=196. RLS: right-to-left shunt.