Repeated measures of St George's Respiratory Questionnaire (SGRQ) total score after 3 years of treatment with fluticasone propionate 500 μg twice daily (FP) or placebo twice daily according to blood eosinophil level

Eosinophils <2%Eosinophils ≥2%
Total patients376375376375
Patients with one or more SGRQ measurements included in the repeated measures analysis1921727579
Patients with SGRQ at 3 years122984846
SGRQ total score54.59±1.10558.69±1.21949.91±1.76455.84±1.790
Change from baseline in SGRQ total score5.59±1.1059.69±1.2190.91±1.7646.83±1.790
Difference in total score: FP versus placebo–4.10 (–7.33– –0.87), p=0.013–5.93 (–10.86– –0.99), p=0.019
  • Data are presented as n, least squares mean±se or difference (95% CI), unless otherwise stated. Repeated measures model with covariates of age, sex and baseline SGRQ total score.