Baseline demographics of study population

Subjects n290
Age years53±15
Female/male n193/97
Height cm166±9
Weight kg69.7±15.5
BMI kg·m−225.2±5.0
Functional capacity
 NYHA functional class I/II/III %16/52/32
 6MWD m456±111
Pulmonary haemodynamics
 Resting heart rate beats·m−173±12
 Resting mPAP mmHg18.3±3.8
 Resting PAWP mmHg7.6±3.3
 Resting TPG mmHg10.7±4.2
 Resting CO L·min−16.0±1.5
 Resting PVR WU1.9±0.9
 Resting TPVR WU3.2±1.0
 Resting RV power W0.30±0.10
Risk factor for pulmonary vascular disease184 (63.4)
 Connective tissue disease52 (17.9)
 History of venous thromboembolism51 (17.6)
 Anorexigens and drugs32 (11.0)
 Miscellaneous49 (16.9)
Risk factor for left heart disease127 (43.8)
  • Data are presented as mean±sd or n (%), unless otherwise stated. BMI: body mass index; NYHA: New York Heart Association; 6MWD: 6-min walk distance; mPAP: mean pulmonary artery pressure; PAWP: pulmonary artery wedge pressure; TPG: transpulmonary gradient; CO: cardiac output; PVR: pulmonary vascular resistance; TPVR: total pulmonary vascular resistance; RV: right ventricle.