Sarcoidosis patients | Healthy subjects | p-value | |
Subjects n | 32 | 40 | |
Age years | 50±13 | 49±13 | 0.700 |
Female | 20 (63) | 27 (68) | 0.457 |
Ethnicity | |||
Afro-Caribbean | 21 (66) | ||
Caucasian | 8 (25) | ||
South Asian# | 2 (6) | ||
Other | 1 (3) | ||
Smoking status | |||
Current | 0 (0) | 0 (0) | |
Ex (<10 pack-years) | 7 (22) | ||
Never | 25 (78) | 40 (100) | |
Organs involved | |||
Lungs | 32 (100) | ||
Skin | 15 (47) | ||
Eyes | 6 (19) | ||
Nervous system | 4 (13) | ||
Bone and joints | 4 (13) | ||
Organs involved n | 2±0 | ||
FEV1 % pred | 72.2±19.1 | 97.0±28.2 | <0.001 |
FVC % pred | 83.7±16.8 | 100.9±29.0 | <0.001 |
TLCO % pred | 66.5±11.5 | ||
Scadding stage | |||
0/I | 8 | ||
II | 9 | ||
III | 4 | ||
IV | 11 | ||
Immunosuppressant¶ | |||
None | 19 (56) | ||
Prednisolone | 10 (29) | ||
Hydroxychloroquine | 3 (9) | ||
Inhaled steroids | 2 (6) | ||
Serum ACE level+ IU·L−1 | 75±37 |
Data presented as n (%) or mean±sd, unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLCO: transfer factor of the lung for carbon monoxide; ACE: angiotensin-converting enzyme. #: patients originating from India, Pakistan or Bangladesh; ¶: immunosuppressant medications were those prescribed at the time of the study; +: normal serum angiotensin-converting enzyme (ACE) level 52 IU·L−1.