TABLE 2

Patient characteristics

Sarcoidosis patientsHealthy subjectsp-value
Subjects n3240
Age years50±1349±130.700
Female20 (63)27 (68)0.457
Ethnicity
 Afro-Caribbean21 (66)
 Caucasian8 (25)
 South Asian#2 (6)
 Other1 (3)
Smoking status
 Current0 (0)0 (0)
 Ex (<10 pack-years)7 (22)
 Never25 (78)40 (100)
Organs involved
 Lungs32 (100)
 Skin15 (47)
 Eyes6 (19)
 Nervous system4 (13)
 Bone and joints4 (13)
Organs involved n2±0
FEV1 % pred72.2±19.197.0±28.2<0.001
FVC % pred83.7±16.8100.9±29.0<0.001
TLCO % pred66.5±11.5
Scadding stage
 0/I8
 II9
 III4
 IV11
Immunosuppressant
 None19 (56)
 Prednisolone10 (29)
 Hydroxychloroquine3 (9)
Inhaled steroids2 (6)
Serum ACE level+ IU·L−175±37
  • Data presented as n (%) or mean±sd, unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLCO: transfer factor of the lung for carbon monoxide; ACE: angiotensin-converting enzyme. #: patients originating from India, Pakistan or Bangladesh; : immunosuppressant medications were those prescribed at the time of the study; +: normal serum angiotensin-converting enzyme (ACE) level 52 IU·L−1.