TABLE 3

Inhaled corticosteroid response after 28 days of therapy in three mast cell subtypes

MCT subtypeMCT/CPA3 subtypep-value
Subjects3019
ΔACQ score−0.6 (−1.4–0.0)−1.2 (−2.3 – −0.7)0.043
ΔFEV1 % predicted10.7 (3.9–19.1)25.1 (7.4–45.7)0.035
ΔPD20AMP3.0 (0.6–5.0)3.5 (2.4–5.7)0.353
ΔFeNO−35.7 (−72.4 – −1.7)−60.1 (−76.7 – −42.4)0.055
  • Data are presented as n or median (interquartile range), unless otherwise stated. ACQ: Asthma Control Questionnaire; FEV1: forced expiratory volume in 1 s; PD20 AMP: provocative dose of AMP causing a 20% fall in FEV1; FeNO: exhaled nitric oxide fraction.