TABLE 2

Summary of correlation analysis with anti-tumour necrosis factor (TNF)-α scintigraphy

Ratio T/B values (20 h/6 h, versus aorta descendens) anti-TNF-α scintigraphySerum TNF-α
Left hilar lymph nodep-valueRight hilar lymph nodep-valueAverage hilar lymph nodesp-valueSubcarinal lymph nodep-valueRight lung parenchyma (carina level)p-valueSerum TNF-αp-value
Serum ACE0.760.0170.730.0250.780.0120.410.270.200.610.800.011
ACE Z-score#0.810.0150.740.0380.810.0140.380.350.0110.980.700.052
sIL-2R0.910.000+0.830.003+0.910.000+0.690.0280.430.220.800.005
BAL CD4/CD8 ratio0.640.0660.730.0270.720.0290.470.210.540.130.110.76
VC−0.290.42−0.120.74−0.210.56−0.430.21−0.490.15−0.0720.84
FEV1−0.480.16−0.390.27−0.450.19−0.570.0880.640.047−0.120.74
Tiffeneau index0.640.046−0.630.0510.660.037−0.620.058−0.540.10−0.280.44
DLCO−0.490.15−0.380.28−0.450.190.770.009−0.560.093−0.320.38
  • Data are presented as r, unless otherwise stated. Bold type represents p<0.05. T/B: target/background; ACE: angiotensin-converting enzyme; sIL-2R: soluble interleukin-2 receptor; BAL: bronchoalveolar lavage; VC: vital capacity; FEV1: forced expiratory volume in 1 s; DLCO: diffusing capacity of the lung for carbon monoxide. #: ACE insertion-/deletion-corrected ACE activity; : FEV1/forced vital capacity×100; +: statistically significant after Bonferroni correction.