Clinical and physiological differences among the computed tomography diagnostic categories

TotalUIPPossible UIPInconsistent with UIPp-value
Sex male/female184/5781/2151/1352/230.227
Age years65.7±8.067.4±7.563.8±7.8*65.0±8.50.01
Duration of illness years2.0±2.12.3±2.11.7±1.72.0±2.30.236
Smoking ever/never175/6682/2042/2251/240.065
Post-walk Borg dyspnoea score#2.9±1.82.9±1.82.8±1.73.0±1.80.85
St George's Respiratory Questionnaire total score#47.0±17.346.1±16.746.0±17.349.1±18.20.449
6-min walking distance m326.9±136.9320.3±157.7356.40±117.4310.9±118.20.124
DLCO % pred37.8±13.435.3±13.641.7±14.8*38.0±11.90.01
FEV1/FVC %77.6±1.977.3±1.677.9±1.677.9±2.30.029
FVC % pred63.8±16.364.8±16.065.6±17.561.0±15.30.192
Total lung capacity L4.0±1.14.1±1.14.2±1.23.7±0.9*0.011
History of antigen exposure13 (5.39)6 (5.88)4 (6.25)3 (4.00)0.491
Gastro-oesophageal reflux symptoms161 (66.8)64 (62.8)44 (68.8)53 (70.7)0.504
  • Data are presented as n, mean±sd or n (%), unless otherwise stated. UIP: usual interstitial pneumonia; DLCO: diffusing capacity of the lung for carbon monoxide; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. #: higher score indicates worse function. *: p<0.05 versus UIP group; : p<0.05 versus possible UIP group.