TABLE 2

Bronchial sensitivity and reactivity indices in subjects with asthma

Non-MC groupMCT subtypeMCT/CPA3 subtypep-value
PD15 4.5% saline mL#9.84±8.468.15±3.784.93±4.790.176
Bronchial reactivity indices
 DRS %·mL–14.83±10.391.12±1.179.90±16.94§0.010
 CIR−0.13±0.88−0.10±0.430.46±0.69+,§0.025
  • Data are presented as mean±sd, unless otherwise stated. PD15: provocative dose of 4.5% hypertonic saline causing a 15% fall in forced expiratory volume in 1 s; DRS: dose–response slope; CIR: continuous index of responsiveness. #: n=3, 6 and 19 for non-MC, MCT and MCT/CPA3, respectively; : n=6, 14 and 24 for non-MC, MCT and MCT/CPA3, respectively.+: p<0.05 compared with non-MC; §: p<0.05 compared with MCT.