TABLE 6

Clinical and physiological differences between concordant and discordant cases

Concordant casesDiscordant casesp-value
Subjects9971
Sex male/female78/2148/230.101
Age years67.5±7.764.9±8.70.036
Duration of illness years2.2±2.11.9±2.10.307
Smokers ever/never80/1948/230.049
Post-walk Borg dyspnoea score#2.92±1.822.91±1.840.99
St George's Respiratory Questionnaire total score#46.6±16.748.3±18.10.53
6-min walking distance m320.0±157.3308.6±12.00.612
DLCO % pred35.0±13.338.2±12.20.114
FEV1/FVC %77.2±1.677.9±2.40.032
FVC % pred64.6±16.261.4±15.50.208
Total lung capacity L4.1±1.13.7±0.90.010
History of antigen exposure6 (6.1)3 (4.1)0.598
Gastro-oesophageal reflux symptoms50 (70.4)62 (62.6)0.371
  • Data are presented as n, mean±sd or n (%), unless otherwise stated. DLCO: diffusing capacity of the lung for carbon monoxide; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. #: higher score indicates poorer function; : statistically significant difference between discordant and concordant cases (p<0.05).