Patient characteristics
| Placebo | PRM-151 | ||||
| 1 mg·kg−1 | 5 mg·kg−1 | 10 mg·kg−1 | All doses | ||
| Subjects | 6 | 6 | 5 | 4 | 14 |
| Age years | 65.5±12.9 | 63.7±8.5 | 70.6±8.3 | 66.5±5.7 | 66.7±7.8 |
| Male | 4 (67) | 5 (83) | 4 (80) | 4 (100) | 13 (87) |
| Race | |||||
| White | 5 (83) | 6 (100) | 5 (100) | 4 (100) | 15 (100) |
| African American | 1 (17) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| BMI kg·m−2 | 28.7±3.1 | 28.6±2.3 | 28.6±4.6 | 28.9±2.7 | 28.7±3.1 |
| Oxygen | 4 (67) | 0 (0) | 1 (20) | 0 (0) | 1 (7) |
| UIP on HRCT | |||||
| No | 2 (33) | 3 (50) | 0 (0) | 0 (0) | 3 (20) |
| Possible | 1 (17) | 1 (17) | 2 (40) | 2 (50) | 5 (33) |
| Definite | 3 (50) | 2 (33) | 3 (60) | 2 (50) | 7 (47) |
| UIP upon lung biopsy | 2 (33) | 3 (50) | 1 (20) | 0 (0) | 4 (27) |
Data are presented as n, mean±sd or n (%). BMI: body mass index; UIP: usual interstitial pneumonia; HRCT: high-resolution computed tomography.