TABLE 2

Sputum inflammatory markers according to bacterial pathogens#

Haemophilus influenzaeStaphylococcus aureusUsual flora
Subjects n9710
Age years11.9 (5.8–16.0)15.8 (10.2–17.9)14.4 (7.5–17.7)
FEV1 % predicted85 (59–99)84 (74–113)90 (58–132)
FVC % predicted93 (89–105)99 (86–109)96 (65–119)
FEF25–75% % predicted70 (24–86)62 (50–96)73 (38–170)
Total cell count ×1061.5 (0.1–25.1)2.1 (0.3–4.2)1.2 (0.3–10.3)
Neutrophils %95.6 (65.0–99.8)92.4 (88–96.8)94.3 (77.3–98.5)
IL-8 ng·mL−1418.7 (4.3–990.9)69.6 (5.4–400.7)206.8 (106.0–508.0)
NE nmol·min−162.3 (1.23–308.7)10.1 (0.3–30.3)4.7 (1.4–113.9)
  • Data are presented as median (range), unless otherwise stated. #: only patients with single pathogens included. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FEF25–75%: forced expiratory flow at 25–75% of FVC; IL: interleukin; NE: neutrophil elastase.