TABLE 2

Reproductive characteristics

	Cohort	Non-asthmatic	Asthmatic	Mean difference (95% CI)	HR (95% CI)	OR (95% CI)	p-value
Subjects	245	149	96
Menarche age years	13.1±1.4	13.1±1.4	13.1±1.4	−0.01 (−0.38–0.35)			0.940
Spontaneous abortions	0.51±0.9	0.52±0.9	0.49±0.8	−0.03 (−0.26–0.20)			0.816
TTP median month^#
Total TTP^¶	38.6	32.3	55.6		0.50 (0.34–0.74)		0.001
TTP in treatment⁺	20.0	17.9	35.6		0.57 (0.39–0.84)		0.004
TTP from inclusion^§	10.0	6.6	13.5		0.56 (0.38–0.81)		0.002
Successful pregnancy rate^ƒ %	52.2	60.4	39.6			0.43 (0.25–0.73)	0.002
Successful pregnancy rate per cycle^ƒ %	13.7	13.5	13.9			0.002 (−0.02–0.02)	0.862
Primary infertility n (%)	150 (61.2)	98 (65.8)	52 (54.2)			1.63 (0.96–2.75)	0.081
Secondary infertility^## n (%)	95 (38.8)	51 (34.2)	44 [45.8]
Child, previous fertility treatment^¶¶: n/N (%)	57/95 (60.0)	33/51 (64.7)	24/44 (54.5)			1.52 (0.67–3.49)	0.402
Semen quality⁺⁺ ×10⁶·mL⁻¹	29.0±0.33	29.0±0.32	29.0±0.33	0.00 (−0.9–0.08)			0.994
Semen motility	2.3±0.5	2.2±0.4	2.3±0.5	0.06 (0.01–0.24)			0.034

Data are presented as n or mean±sd, unless otherwise stated. Data in bold is statistically significant. ^#: the results for total time to pregnancy (TTP) in total, in treatment and from inclusion were adjusted for confounders; ^¶: total TTP from trying to conceive naturally to successful pregnancy in fertility treatment or stopping treatment; ⁺: TTP treatment from the first until the last treatment cycle in fertility treatment; ^§: TTP from inclusion in the study until the last treatment cycle in the month; ^ƒ: successful pregnancy rate and successful pregnancy rate per treatment cycle occurring during the treatment period from December 2011 to December 2014; ^##: had a child before participating in the study; ^¶¶: conception of first child after fertility treatment, the percentages describe the amount of secondary infertility who had fertility treatment to conceive their first child; ⁺⁺: after purification (calculated in log).