TABLE 12

Follow up of Aspergillus nodules after resection surgery

PopulationIntentionInterventionSoRQoERef.Comment
Aspergillus nodule not treated with antifungal therapyTo identify progression early and/or carcinoma of lung if multiple lesions3–6 months clinical follow up with low dose imaging, inflammatory markers and Aspergillus IgG / precipitinsAIII[125, 141]Not necessary if entire single nodule resected
Post-lobectomy/  pneumectomyTo detect recurrence early3–6 month, then 6-monthly for 3 years with inflammatory markers and Aspergillus IgG/precipitinsAIII[125]No predictors of recurrence yet described; full re-evaluation if consistent increase in Aspergillus IgG titres
  • SoR: strength of recommendation; QoE: quality of evidence.