PAH | PVOD | Crude OR (95% CI) | p-value | Adjusted OR# (95% CI) | p-value | |
Subjects n | 65 | 33 | ||||
Trichloroethylene | ||||||
Lifetime exposure | 4 (6.2) | 12 (36.4) | 8.7 (2.5–30.0) | 0.001 | 6.4 (1.3–30.4) | 0.020 |
10-year lag exposure | 2 (3.1) | 12 (36.4) | 18.0 (3.7–87.1) | <0.0001 | 9.8 (1.5–62.3) | 0.015 |
White spirits | ||||||
Lifetime exposure | 14 (21.5) | 13 (39.4) | 2.4 (0.95–5.9) | 0.065 | 1.4 (0.4–4.8) | 0.538 |
10-year lag exposure | 12 (21.5) | 13 (39.4) | 2.8 (1.1–7.3) | 0.028 | 1.6 (0.5–5.2) | 0.471 |
Benzene | ||||||
Lifetime exposure | 2 (3.1) | 3 (9.1) | 3.2 (0.5–19.9) | 0.222 | 1.4 (0.2–11.8) | 0.752 |
10-year lag exposure | 1 (1.5) | 3 (9.1) | 6.4 (0.6–64.1) | 0.114 | 2.5 (0.2–32.5) | 0.484 |
Petroleum solvents | ||||||
Lifetime exposure | 1 (1.5) | 3 (9.1) | 6.4 (0.6–64.1) | 0.114 | 2.3 (0.2–29.4) | 0.529 |
10-year lag exposure | 1 (1.5) | 3 (9.1) | 6.4 (0.6–64.1) | 0.114 | 2.3 (0.2–29.4) | 0.529 |
Data are presented as n (%), unless otherwise stated. PAH, pulmonary arterial hypertension. #: adjusted for age, sex and smoking history (pack-years).