TABLE 3

Characteristics of tuberculosis (TB)-exposed children at baseline evaluation stratified by diagnosis of either active TB disease or other disease

All subjectsActive TBOther diseasep-value#
Subjects15035115
Age years6 (3–9)4 (2–7)7 (4–9)0.004
 <5 years55 (37)21 (60)34 (30)0.001
Sex male76 (51)15 (43)61 (53)0.291
Clinical features
 Symptoms
  Cough lasting ≥2 weeks105 (70)27 (77)78 (68)0.292
  Weight loss80 (53)21 (60)59 (51)0.367
  Night sweats51 (34)16 (46)35 (30)0.095
  Fever63 (42)19 (54)44 (38)0.093
  Fatigue/malaise32 (21)11 (31)21 (18)0.096
 Signs
  Lymphadenopathy28 (19)12 (34)16 (14)0.007
  Abnormal chest radiography107 (71)28 (80)79 (69)0.195
  BCG vaccination99/141 (70)21/33 (64)78/108 (72)0.345
  BMI-for-age z-score <−2 sd44 (29)13 (37)31 (27)0.259
  Height-for-age z-score <−2 sd20 (13)4 (11)16 (14)0.705
Tests of TB infection
 TST ≥10 mm82 (55)17 (49)65 (57)0.408
 IFN-γ value ≥155.0 pg·mL−1103 (69)25 (71)78 (69)0.687
  • Data are presented as n, median (interquartile range), n (%) or n/N (%), unless otherwise stated. BCG: bacille Calmette–Guerin; BMI: body mass index; TST: tuberculin skin test; IFN: interferon. #: active TB disease versus other disease.