Multivariate analysis of the association of plasma CC16 levels with chronic bronchitis, rapid decline in forced expiratory volume in 1 s (FEV1) and their interaction
| PE (se) | p-value | |
| Age | 0.018 (0.002) | <0.0001 |
| Female | −0.249 (0.042) | <0.0001 |
| Hispanic | −0.026 (0.048) | 0.589 |
| Body mass index | 0.002 (0.003) | 0.430 |
| Pack years | −0.001 (0.001) | 0.106 |
| Baseline smoker | −0.328 (0.040) | <0.0001 |
| Rapid decline | −0.112 (0.045) | 0.012 |
| Chronic bronchitis | −0.134 (0.055) | 0.015 |
| COPD | −0.245 (0.054) | <0.0001 |
| Rapid decline + chronic bronchitis | 0.015 (0.078) | 0.849 |
| Chronic bronchitis + COPD | 0.108 (0.085) | 0.203 |
Data are presented as point estimates with standard errors. Multivariable linear regression adjusted for age, sex, Hispanic ethnicity, baseline body mass index, pack years of smoking, smoking status at baseline, rapid FEV1 decline status, baseline chronic bronchitis and the interaction of baseline chronic bronchitis and rapid FEV1 decline status. COPD: chronic obstructive pulmonary disease.