TABLE 5

Association between maternal body mass index and number of consultations and prescriptions for wheezing illnesses until the age of 5 years in the offspring, stratified by maternal atopy

ModelNo maternal atopyMaternal atopyp-value interaction
Subjects nIRR (95% CI)p-valueSubjects nIRR (95% CI)p-value
Wheezing illnesses
 16451.010 (0.975–1.046)0.573881.062 (1.020–1.105)<0.010.07
 25371.003 (0.961–1.048)0.883361.042 (0.991–1.095)0.110.15
 33240.939 (0.881–1.001)0.052001.027 (0.957–1.102)0.460.02
 44310.995 (0.946–1.046)0.832741.042 (0.985–1.103)0.150.08
Inhaled corticosteroids
 16541.046 (1.008–1.086)0.023971.108 (1.062–1.155)<0.010.05
 25451.051 (1.005–1.099)0.033431.126 (1.068–1.186)<0.010.08
 33281.011 (0.944–1.083)0.752051.135 (1.054–1.223)<0.010.08
 44360.992 (0.932–1.055)0.792811.135 (1.069–1.205)<0.01<0.01
Short-acting β2-agonists
 16541.024 (0.995–1.054)0.113971.071 (1.034–1.109)<0.010.05
 25451.035 (1.001–1.070)0.053431.086 (1.042–1.133)<0.010.22
 33280.987 (0.933–1.043)0.632051.110 (1.050–1.174)<0.01<0.01
 44361.037 (0.998–1.077)0.062811.084 (1.034–1.135)<0.010.24
  • IRR: incidence rate ratio; 1: univariable; 2: daycare, breastfeeding, older siblings, smoke exposure during pregnancy, pet keeping, socioeconomic status, ethnicity and maternal age; 3: all variables of model 2 and weight and height at 5-year visit; 4: all variables of model 2 and resistance of the respiratory system.