Demographics, pulmonary function and blood gas analysis
| ILD | Controls | p-value | |
| Subjects n | 27 | 11 | |
| Age years | 65.2±2.4 | 61.5±2.0 | 0.258 |
| Female % | 52 | 54 | 0.972 |
| Caucasian % | 96 | 100 | 1.000 |
| Positive smoking history % | 59 | 55 | 0.534 |
| Smoking history pack-years | 35.1±11.4 | 25.8±13.6 | 0.612 |
| BMI kg·m−2 | 27.8±1.1 | 30.0±1.3 | 0.081 |
| Radiographic pattern of ILD n | |||
| UIP | 18 | ||
| NSIP | 3 | ||
| OP | 2 | ||
| Smoking-related fibrosis | 1 | ||
| Lymphocytic interstitial pneumonia | 1 | ||
| Radiation-induced fibrosis | 1 | ||
| Sarcoidosis | 1 | ||
| FEV1 % predicted | 69±3 | 102±5 | <0.001 |
| FVC % predicted | 68±3 | 105±5 | <0.001 |
| FEV1/FVC % predicted | 103±2 | 98±2 | 0.055 |
| RV % predicted | 66±4 | 92±6 | 0.004 |
| TLC % predicted | 69±3 | 102±3 | <0.001 |
| RV/TLC % predicted | 99±4 | 89±6 | 0.213 |
| DLCOHb % predicted | 45±4 | 94±6 | <0.001 |
| Hb g·dL−1 | 12.8±0.3 | 13.5±0.3 | 0.118 |
| PaO2 mmHg | 82±3 | 101±4 | <0.001 |
| SO2 % | 96.0±0.4 | 97.6±0.2 | 0.013 |
Data are presented as mean±sem unless otherwise stated. ILD: interstitial lung disease; BMI: body mass index; UIP: usual interstitial pneumonia; NSIP: nonspecific interstitial pneumonia; OP: organising pneumonia; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; RV: residual volume; TLC: total lung capacity; DLCOHb: diffusing capacity of the lung for carbon monoxide corrected for haemoglobin; Hb: haemoglobin; PaO2: arterial oxygen tension; SO2: oxygen saturation. Bold indicates statistical significance.