TABLE 3

Diagnostic accuracy of the association of the two criteria: mPAPmax >30 mmHg and TPRmax >3 WU for entire study population and subgroups#

 nSensitivity (95% CI)Specificity (95% CI)NPVPPVAccuracy
All1690.93 (0.86–0.96)1.0 (0.95–1.0)0.9110.96
Sex
 Male550.82 (0.68–0.96)1.0 (0.88–1.0)0.8410.90
 Female1140.93 (0.87–0.99)1.0 (0.91–1.0)0.8910.96
Age
 >50 years950.94 (0.89–0.99)1.0 (0.87–1.0)0.8710.96
 ≤50 years740.81 (0.67–0.95)1.0 (0.92–1.0)0.8710.92
Diagnosis
 PVD490.94 (0.84–0.98)1.0 (0.95–1.0)0.9210.95
 LHD520.92 (0.82–0.97)1.0 (0.95–1.0)0.9410.97
  • #: The test was considered positive only if both criteria mPAPmax >30 mmHg and TPRmax >3 WU were satisfied. mPAPmax: mean pulmonary artery at maximal exercise; TPRmax: total pulmonary resistance at maximal exercise; NPV: negative predictive value; PPV: positive predictive value; PVD: pulmonary vascular disease; LHD: left heart disease.