TABLE 4

Reclassification table and net reclassification improvement (NRI) for Global Lungs Initiative lower limit of normal (GLI-LLN)# versus fixed cut-off for all-cause mortality and hospitalisation

AllReclassified upReclassified down+NRI (95% CI) %p-value
Mortality
 Dead164029−17.7 (−24.2– −12.1)<0.01
 Alive24704417.8 (13.3–23.1)<0.01
 Total4110.001 (−0.08–0.08)§0.99
Hospitalisation
 With203039−19.2 (−25.2– −14)<0.001
 Without20303416.8 (11.9–22.5)<0.001
 Total406−0.02 (−0.10–0.05)§0.63
  • Data are presented as n, unless otherwise stated. #: 5th percentile of Global Lungs Initiative 2012 z-scores distribution; : if no airflow limitation by fixed cut-off, but airflow limitation by GLI-LLN; +: if airflow limitation by fixed cut-off, but no airflow limitation by GLI-LLN; §: total NRI expressed as a proportion [19].