Main somatic mutation profile according to exposure to passive smoking in univariate analysis
| EGFR# | KRAS¶ | ALK+ | ||||
|---|---|---|---|---|---|---|
| Mutations n (%) | p-value | Mutations n (%) | p-value | Rearrangements n (%) | p-value | |
| Exposure to passive smoking | ||||||
| Never | 46 (46, 95% CI 36–56) | 0.486 | 6 (7, 95% CI 3–15) | 0.867 | 7 (13, 95% CI 6–26) | 0.726 |
| Ever | 81 (41, 95% CI 34–49) | 12 (7, 95% CI 4–13) | 13 (11, 95% CI 6–19) | |||
| Cumulative duration of exposure | ||||||
| Never | 46 (46) | 0.866 | 6 (7) | NC | 7 (13) | NC |
| ⩽20 years | 28 (44) | 4 (7) | 2 (5) | |||
| 20–30 years | 28 (42) | 4 (7) | 4 (10) | |||
| >30 years | 25 (39) | 4 (8) | 6 (18) | |||
| Missing | 3 | 1 | 2 | |||
| Time of exposure | ||||||
| Never | 53 (45) | 0.799 | 8 (8) | 0.940 | 7 (11) | 0.522 |
| Childhood | 45 (41) | 6 (7) | 10 (15) | |||
| Adulthood only | 29 (43) | 4 (7) | 3 (8) | |||
| Workplace exposure | ||||||
| Never | 105 (43) | 0.942 | 15 (7) | 0.643ƒ | 18 (12) | 0.442ƒ |
| Ever | 22 (42) | 3 (7) | 2 (8) | |||
| Domestic exposure | ||||||
| Never | 53 (45) | 0.542 | 8 (8) | 0.458ƒ | 7 (11) | 0.533ƒ |
| Ever | 74 (41) | 10 (7) | 13 (12) | |||
| Childhood exposure | ||||||
| Never§ | 82 (44) | 0.550 | 12 (7) | 0.784 | 10 (10) | 0.320 |
| Ever | 45 (41) | 6 (7) | 10 (15) | |||