Plasma levels of inflammatory proteins in chronic thromboembolic pulmonary hypertension (CTEPH) patients and healthy subjects
| Healthy controls | CTEPH | p-value | |
| Subjects n | 20 | 20 | |
| CRP mg·L−1 | 2.4 (1.6–3.4) | 6.4 (4.3–9.4) | 0.0005 |
| IL-1β pg·mL−1 | 0.12 (0.09–0.15) | 0.12 (0.07–0.20) | 0.86 |
| IL-6 pg·mL−1 | 0.66 (0.43–1.02) | 1.17 (0.63–2.20) | 0.11 |
| IL-10 pg·mL−1 | 0.25 (0.17–0.37) | 0.71 (0.37–1.32) | 0.006 |
| MCP-1 pg·mL−1 | 109 (91–130) | 158 (134–186) | 0.002 |
| MIP-1α pg·mL−1 | 8.7 (7.3–10.5) | 14.2 (11.6–17.2) | 0.0006 |
| MMP-9 pg·mL−1 | 1.29 (0.49–3.38) | 6.70 (5.50–8.17) | 0.0009 |
| VEGF-A pg·mL−1 | 32.5 (18.4–57.4) | 17.8 (5.5–57–9) | 0.09 |
Data are presented as geometric mean (95% CI), unless otherwise stated. Bold type represents statistical significance. CRP: C-reactive protein; IL: interleukin; MCP: monocyte chemotactic protein; MIP: macrophage inflammatory protein; MMP: matrix metalloproteinase; VEGF: vascular endothelial growth factor.