Characteristics of subjects in the three patient groups

Cystic fibrosisHealthy controlsNon-cystic fibrosis bronchiectasis
Subjects n40108
Age years23±1422±756±17
Sex male/female19/214/65/3
CRP mg·dL−10.8±0.5n.d.1.2±0.8
WBC 109·L−111±77±410±6
Total IgE kUI·L−149±34n.d.44±27
FEV1 % pred66±15n.d.55±20
MEF25 % pred39±27n.d.29±16
Neutrophils in sputum %82±2915±958±31
Eosinophils in sputum %3±2.80.6±0.41.9±0.7
Pseudomonas aeruginosa18n.d.2
Aspergillus spp.22n.d.3
IgE specific to Aspergillus fumigatus kU·L−12.3±1.6n.d.0.8±0.5
IgG specific to A. fumigatus mg·L−159±35n.d.37±19
A. fumigatus precipitins2/40n.d.0/3
Candida spp.20n.d.2
Aspergillus spp. and Candida spp. co-colonisation10n.d.0
Staphylococcus aureus11n.d.0
Haemophilus influenzae4n.d.0
Achromobacter xylosoxidans5n.d.0
Stenotrophomonas maltophilia6n.d.0
Inhaled antibiotics1802
Inhaled corticosteroids1602
ΔF508 homozygous/heterozygous/other20/13/7n.d.n.d.
  • Data are presented as n or mean±sd, unless otherwise stated. CRP: C-reactive protein; WBC: white blood cells; FEV1: forced expiratory volume in 1 s; % pred: % predicted; MEF25: maximum expiratory flow at 25% of forced vital capacity; n.d.: not determined.